六九色堂

April 1, 2021

UCalgary researcher studies link between ADHD and accelerated cognitive aging

Brandy Callahan hopes results will inform dementia prevention programs in the future
Brandy Callahan
Brandy Callahan

Throughout her clinical practice, Dr. Brandy Callahan, PhD, has encountered many individuals worried about cognitive changes, specifically dementia

Working with these patients led her to the conclusion that many of them also suffered from psychiatric illnesses that had similar symptoms to dementia. This, in turn, led Callahan, a clinical neuropsychologist and assistant professor in the 六九色堂鈥檚 to question what the best way is to measure cognition and what is the best way to tease apart a psychiatric issue from a cognitive one.

鈥淚 became confronted [with]the fact that, textbook-wise, what we are often asked to evaluate doesn鈥檛 map on well with the clients we see in real life,鈥 says Callahan, who is also a member of the 鈥淚 was being asked to evaluate clients complaining of cognitive impairment, but, when doing a history with them, I realized that they had many, many years of other things going on.鈥

Understand risk factors for later dementia

The questions raised from evaluating clients underlie Callahan鈥檚 research which is focused on whether certain conditions, specifically attention deficit hyperactivity disorder (ADHD), might pose risk factors for later dementia. According to Callahan, there听are many things that need to be taken into consideration when evaluating the impact of ADHD on cognition, such as its severity, how long it鈥檚 been present and an individual鈥檚 coping mechanisms.

The impacts of ADHD have been well researched, and it is recognized that individuals with ADHD can experience cognitive symptoms such as forgetfulness, as Callahan has found in her research, but the impacts of ADHD on cognition later in life is still unclear.

Callahan鈥檚 research on ADHD and dementia lies at the intersection of psychiatry, neurodegeneration and normal aging, with Callahan鈥檚 specialty being geriatric neuropsychology.

How our thinking skills change as we age

Through her research, Callahan says she hopes to determine whether the suspected relationship between ADHD and dementia is evident. This research will improve understanding of the relationship between mental health and cognitive aging, which broadly refers to changes in thinking skills that occur normally as we age.

鈥淥ther research groups have, in the past decade, published research suggesting that there might be a link between ADHD and accelerated cognitive aging, and so a lot of the questions that I am seeking to answer are: is this relationship real and, if it is real, what鈥檚 the mechanism driving it?鈥 Callahan says.

Shift toward prevention

As mentioned at the 2019 researchers have shifted their resources toward finding ways to prevent dementia on the front end, rather than cure it on the back end. Callahan say she hopes that, regardless of her final research findings, her results can be used to inform dementia prevention programs in the future.

鈥淚 think there are lots of factors that play into how a person ages, even if they have an existing issue,鈥 she says.

about Callahan鈥檚 study.

Brandy Callahan is a听Tier II Canada Research Chair in Adult Clinical Neuropsychology.