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Medical Science MDSC

Instruction offered by members of the Faculty of Medicine.

Students contemplating taking any of the undergraduate medical science courses are advised to contact the course coordinator(s) through the Bachelor of Health Sciences program office. Students contemplating taking any of the graduate-level (600- and up) Medical Science courses are advised to contact the course coordinator through the Graduate Science Education office.

Medical Science 101 E(10 hours)

(formerly Medical Science 001)

Biomedical Methods I: DNA and Protein Analysis

A hands-on introduction to methods used in the analysis of nucleic acids and proteins, including isolation, purification and quantitation, electrophoresis and blotting, polymerase chain reaction and sequencing.

Prerequisites: Admission to the BHSc Honours program.

NOT INCLUDED IN GPA

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Medical Science 102 E(10 hours)

(formerly Medical Science 002)

Biomedical Methods II: Cell Culture and Microscopy

A hands-on introduction to the techniques of cell culture and light and fluorescence microscopy.

Prerequisites: Admission to the BHSc Honours program.

NOT INCLUDED IN GPA

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Junior Courses

Medical Science 203 H(3-0)

Inquiry I Introduction to Inquiry

Students will develop reading and academic writing skills. Through reading and writing assignments, the course will also introduce students to the interdisciplinary scope of health research.

Prerequisites: Admission to the BHSc Honours program.

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Medical Science 205 H(3-0)

Inquiry II

Students will develop their critical thinking skills and their ability to write logically, well-argued research papers. Students will learn the fundamentals of logical reasoning as well as how to analyze theoretical issues in science, medicine, and philosophy.

Prerequisites: Medical Science 203 and admission to the BHSc Honours program.

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Senior Courses

Medical Science 307 H(3-0)

Science, Philosophy & Society

A survey of underlying ideas concerning the objectives, methods, ambitions and responsibilities of the natural and social sciences.

Prerequisites: Second year or higher in the BHSc program or consent of the Faculty.

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Medical Science 308 F(6-0)

Inquiry III

An introduction to the questions, methods and research techniques used across the different majors of Biomedical Sciences, Bioinformatics and Health and Society. Students will attend sessions that will support the development of a broad perspective on health issues as well as weekly modules on the Philosophy of Science.

Prerequisites: Medical Science 205 and admission to the BHSc Honours program.

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Medical Science 341 H(4-1T)

Principles of Human Genetics

Introduction to principles in human genetics including Mendelian and chromosomal basis of inheritance, chromosomal abnormalities, pedigree analysis, mutations, and molecular, metabolic, population and clinical genetics. Studies of model organisms and genomics will be included as required. Incorporates web- and problem-based learning to establish analytical skills in genetics.

Prerequisites: Enrolment in the BHSc program or consent of the Faculty.

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Medical Science 351 H(3-2T)

Honours Cellular and Molecular Biology

Introduction to principles in cellular and molecular biology. Emphasizes how structure underlies and determines function in the cell and how complex processes are organized and regulated at the molecular level.

Prerequisites: Medical Science 341 and enrolment in the BHSc program, or consent of the Faculty.

Corequisites: Biochemistry 393.

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Medical Science 397 H(0-4)

Independent Studies in Health Sciences

Guided work fostering independent thought, practical research and the completion of written reports for first and second year BHSc students. After consultation with a Departmental faculty member who will supervise the chosen problem, an approval form obtained from the BHSc office must be signed by the Associate Dean (USE) before a student can be registered.

Prerequisites: First or second year standing and consent of the BHSc Department.

MAY BE REPEATED FOR CREDIT

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Medical Science 401 H(3-0)

Bioinformatics

This introductory course will familiarize students with algorithms and computational techniques for bioinformatics applications. Topics to be covered include algorithm and search engines for the analysis of nucleic acid and protein sequences and structures; machine learning techniques for biological data analysis; systems biology approaches for computational modeling.

Prerequisites: One full-course equivalent in Computer Science at the 300 level or one full-course equivalent in Biological Sciences at the 300 level or consent of the Department.

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Medical Science 402 F(3-3)

Organismal Biology

Organismal structure from the cellular to the organism level focusing on vertebrates with a particular emphasis on humans. Topics covered include cell biology, histology, vertebrate development and anatomy. This course is inquiry based and will consist of lectures, small group sessions and interactive laboratory sessions.

Prerequisites: Enrolment in the BHSc program, Biology 231, and Medical Science 351; or consent of the Faculty.

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Medical Science 404 F(3-0)

Integrative Human Physiology

Physiology is defined as the study of how living organisms function and encompasses the integration of processes from molecules to the whole-organism. Provides fundamental principles and concepts about the physiology of the major human organ systems. Each Unit is coordinated and taught by published scholars.

Prerequisites: Enrolment in the BHSc program or consent of the Faculty.

Note: Lectures run concurrently with Medical Science 604 and will have separate and less strenuous expectations than 604.

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Medical Science 407 H(3-1T-2)

Statistics and Research Design in Health Sciences

An introduction to the study of research design and statistical analysis including a broad overview of the variety of methods for research in health sciences. Students will be introduced to a variety of research tools through lecture and tutorial components.

Prerequisites: Enrolment in the BHSc program.

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Medical Science 408 F(6-0)

Inquiry IV

An introduction to the research methods utilized in the Health Sciences. Students will begin to develop the knowledge and skills necessary to conduct research in their respective fields. The importance of research design, qualitative, quantitative and mixed methods and the theoretical constructs that inform these approaches will be emphasized.

Prerequisites: Medical Science 308 and admission to the BHSc Honours program.

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Medical Science 409 H(3-0)

Brain and Society

Topics will include neuronal mechanisms of addiction, neuronal mechanisms of learning and memory, aging in the human brain and behavioural consequences and mind/brain dichotomy.

Prerequisites: Enrolment in the BHSc program.

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Medical Science 501 H(3-0)

(Biology 501)

Principles and Mechanisms of Pharmacology

Basic principles of pharmacology, with specific emphasis on receptor signaling mechanisms.

Prerequisites: Enrolment in the BHSc program, Biochemistry 443, and one of Zoology 461, 463, or Medical Science 404; or consent of the Faculty.

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Medical Science 503 H(3-0)

(Biology 503)

Pharmacology of Organ Systems

Pharmacology of the nervous, cardiovascular, renal and immune systems, as well as anti-cancer therapies. Principles of toxicology.

Prerequisites: Medical Science 501 (Biology 501) or consent of the Faculty.

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Medical Science 507 H(3-3)

Special Problems in Medical Science

Lectures, seminars, term papers and training in theoretical and/or laboratory methods. After consultation with a faculty member who will supervise the chosen problem, an approval form obtained from the Graduate Sciences Education Office must be signed by the Associate Dean (Graduate Sciences Education) before a student can register.

Prerequisites: Consent of the BHSc department.

MAY BE REPEATED FOR CREDIT

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Medical Science 508 2xF(0-6)

Research Project

Capstone research course in the BHSc to be conducted through any one of the basic research departments. Students would be expected to spend a minimum of 15 hours/week conducting research. Culminates with a Research Symposium Day during which students present and defend their research before an audience of peers and mentors, share their research with the faculty and staff at large through poster presentations and submit a written research thesis.

Prerequisites: After consultation with a faculty member who will supervise the chosen problem, an approval form obtained from the BHSc office must be signed by the Associate Dean (Undergraduate Science Education) before a student can register.

Note: This course is worth 2.0 FCE and is only offered over two sessions.

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Medical Science 509 H(3-3)

Proteomics

An introductory course to familiarize students with techniques used for protein identification and proteome analysis, including one and two-dimensional gel electrophoresis, mass spectrometry and the databases and search engines used in the identification of expressed proteins.

Prerequisites: Biochemistry 443 and Biology 331.

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Medical Science 511 H(3-0)

Instrumental Analysis

An overview of the analytical laboratory instruments used in research and the diagnosis and treatment of human disease.

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Medical Science 515 H(3-0)

(Biology 515)

Cellular Mechanisms of Disease

The cellular and molecular mechanisms underlying basic human disease processes and how these can be influenced by lifestyle and environmental factors. The ways in which this knowledge can be used in the laboratory diagnosis of disease.

Prerequisites: Biochemistry 443 and Biology 331.

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Medical Science 528 F(0-6)

Independent Studies in Medical Science

Original and independent thought, practical research and the completion of written and oral reports. After consultation with a faculty member who will supervise the chosen problem, an approval form obtained from the Graduate Sciences Education Office must be signed by the Associate Dean (Graduate Sciences Education) before a student can register.

Prerequisites: Consent of the BHSc department.

MAY BE REPEATED FOR CREDIT

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Medical Science 541 H(3-0)

(Medical Science 641.01)

Advanced Genetics I

Historical papers will illustrate the foundations of modern genetic principles. Topics including the chromosomal theory of inheritance, the role of pairing and recombination for chromosomal disjunction during meiosis, cytogenetics, the nature of dominant mutations, genetic screens and genetics analysis of developmental pathways. Material covered is drawn from model organisms and humans. Students will be evaluated on class participation, and two oral and one written presentation on assigned papers.

Prerequisites: Medical Science 341 or Biology 311 and consent of the faculty.

Note: Lectures run concurrently with Medical Science 641.01 and will have separate and less strenuous expectations than 641.01.

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Medical Science 543 H(3-0)

(Medical Science 641.03)

Advance Genetics II

An advanced course in molecular genetic analysis. Topics will vary from year to year, but may include identification of the structure, transmission, mutation and molecular pathology of human genes, the use of experimental organisms (chick, fish, fly, mouse, worm) to model human genetic diseases, and molecular studies of human populations and evolution. The focus will be upon applied molecular genetics with recurring emphasis on the theme of relevance to issues in health and society.

Prerequisites: Medical Science 341, 402 or permission of the instructor. Previous completion of Medical Science 541 is suggested but not required.

Note: Lectures run concurrently with Medical Science 641.03 and will have separate and less strenuous expectations than 641.03.

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Medical Science 545 H(3-0)

(Medical Science 641.04)

Genomics

Prerequisites: Medical Science 341 or Biology 311 and consent of the faculty.

Note: Lectures run concurrently with Medical Science 641.04 and will have separate and less strenuous expectations than 641.04.

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Medical Science 561 H(3-0)

(Cellular, Molecular and Microbial Biology 561)

Cancer Biology

Advances in methodology and in theoretical concepts have permitted continuing breakthroughs in our understanding of the organismal, cellular and molecular biology of cancer cells, and in the development of novel strategies for cancer prevention, diagnosis and treatment. These advances will be presented in a comprehensive overview of cancer including issues of demographics and incidence, causation and detection, origins and progression and therapeutic approaches. Emphasis will be placed on the cell and molecular biology of cancer and on the interaction of the cancer cell with the host organism.

Prerequisites: Biochemistry 443, Biology 331, and Cellular, Molecular and Microbial Biology 411.

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Graduate Courses

Medical Science 603 H(3-1)

(Biology 603)

Biology of Laboratory Animals

The course is based on the Canadian Council of Animal Care Syllabus "Basic Principles of Laboratory Animal Science for Research Scientists." In addition to the study of common, research, farm and exotic animals, topics covered include ethical considerations, regulation and legislation, animal models, animal facilities and husbandry, hazard control, surgery, anaesthesiology, euthanasia and post-mortem examinations. Practical sessions will provide experience in handling and restraint of specific laboratory animals, injections, blood collection, anaesthesiology and surgery.

Prerequisites: Consent of the Faculty.

Note: Enrolment in this course is restricted to graduate students who will do research utilizing animals.

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Medical Science 604 F(3-3)

Integrative Human Physiology

Physiology is the study of how living organisms function and encompasses the integration of processes from molecules to the whole-organism. Designed to provide the student with fundamental principles and concepts about the normal function of the major human organ systems. At the end of this course, the student should be well equipped to apply his/her acquired knowledge to solve complex physiological problems related to integrative human physiology.

Prerequisites: Consent of the Faculty.

Note: Lectures run concurrently with Medical Science 404 and will have separate and more strenuous expectations than 404.

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Medical Science 605 H(3-0)

(Computer Science 605)

Information Storage and Processing in Biological Systems

Examination of complex biological systems; concepts and fundamentals of biological solutions to information storage and processing: modelling and computer simulation of biological systems; information storage in biological molecules; genetic networks; hierarchical organization of biological information processing in signal transduction, development, evolution, and ecology; biological control systems.

Prerequisites: Consent of the Faculty.

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Medical Science 609 H(3-0)

Gene Expression

The flow of genetic information from DNA to final protein product. The subject will be covered in two courses offered in alternating years: gene structure and regulation of transcription, including gene structure and organization, chromatin structure, regulation of transcription and post-translational processing; and the activity of genes during development including stored messenger ribonucleoprotein particles and translational control in gametes, the switch from maternal to zygote genome control of development in early embryos and the molecular basis of morphogenesis and differentiation.
609.02. Genes and Development

Prerequisites: Medical Science 537 (Biochemistry 537) or equivalent and consent of the Faculty.

Note: Credit for both Medical Science 609.01 and 607.01 will not be allowed.

Note: Credit for both Medical Science 609.02 and 751.14 will not be allowed.

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Medical Science 612 F(3-1S)

Medical Microbiology

The basic principles of medical microbiology and the pathogenesis of infectious disease and of clinically important microbial pathogens including bacteria, viruses, parasites and fungi. Recent concepts will be described and students will be expected to present and critically discuss research advances of their choosing from the current research literature.

Prerequisites: Cellular, Molecular and Microbial Biology 241 and 343 or equivalent or consent of the Faculty.

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Medical Science 613 H(3-0)

Advanced Studies in Microbiology

Specialized topics including basic principles of infection; spread, prevention and control of infectious diseases; mechanisms of and approaches to study bacterial pathogenesis; mechanism, methodology and modelling of gene expression.
613.01. Epidemiology of Infectious Diseases
613.02. Pathogenesis of Microbial Disease
613.05. Regulation of Gene Expression in Bacteria

Prerequisites: Medical Science 612 or Cellular, Molecular and Microbial Biology 421 or 521 or consent of the Faculty.

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Medical Science 619 H(3-0)

Neurosciences

Introductory neuroscience courses covering aspects of cellular, molecular, and systems physiology, neuroanatomy, and neurodevelopment.
619.01. Cellular and Molecular Neuroscience
619.02. Systems Neuroscience
619.03. Developmental Neuroscience
619.04. Neuroanatomy

Prerequisites: Consent of the Faculty.

Note: Medical Science 619.02 is open only to graduate students registered in the Neuroscience graduate program or other graduate students approved by the course coordinator. Not open to undergraduate students.

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Medical Science 621 H(3-0)

Principles of Drug Action

The action of chemicals and drugs on biological systems ranging from subcellular particles to the intact organism.
621.01. Basic Principles of Pharmacology

Prerequisites: Zoology 461 and Biochemistry 441 and 443 or consent of the Faculty.

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Medical Science 623 H(3-1T)

Respiratory Science

Respiratory physiology; aspects of morphology, biochemistry and pharmacology necessary to an understanding of respiration.
623.01. Pulmonary Mechanics and Gas Exchange
623.02. Respiratory Muscle Physiology and Control of Breathing
623.03. Respiratory Science: Basic
623.04. Respiratory Science: Applied

Prerequisites: Zoology 463 or 465 or consent of the Faculty.

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Medical Science 627 H(3-0)

Endocrinology

Normal endocrine physiology and biochemistry. Mechanisms and principles of departure from normal endocrine homeostasis.
627.03. Selected Topics in Advanced Endocrinology

Prerequisites: Zoology 597 or consent of the Faculty.

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Medical Science 629 H(3-0)

Cardiovascular Dynamics

Includes topics such as basic physiologic mechanisms including excitation-contraction coupling, mechanics, energetics, and cardiovascular control; major diseases entities as a means of illustrating pathologic alterations in normal physiologic mechanisms; or a systematic in-depth examination of the chemicals that affect the cardiovascular system.
629.01. Cardiovascular Physiology
629.02. Cardiovascular Pathophysiology
629.03. Cardiovascular Pharmacology

Prerequisites: Consent of the Faculty.

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Medical Science 631 H(3-0)

Muscle Physiology

Contractile processes, excitation-contraction coupling, the control of contraction and energetics in smooth, cardiac and skeletal muscle. Molecular studies of the contractile process and of the process of excitation contraction coupling.

Prerequisites: Consent of the Faculty.

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Medical Science 633 H(3-0)

The Kidney

Advanced courses detailing the functional organization of the kidney at all levels, from cell to intact organism. Topics encompass basic physiological principles and their relevance to experimental medicine and therapeutics, as well as the study of disease processes, which impact kidney function.
633.01. Renal Physiology
633.02. Renal Pathophysiology

Prerequisites: Medical Science 604 or equivalent or consent of the Faculty.

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Medical Science 635 H(3-0)

Psychosocial Oncology

Focuses on developing the understanding in health care practitioners of the central concepts related to caring for cancer patients and their families. In doing so, makes use of lectures, readings, video tapes, case discussions, and current research.

Prerequisites: Consent of the Faculty.

Note: Credit for both Medical Science 635 and 645.14 will not be allowed.

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Medical Science 637 H(3-0)

Gastrointestinal Physiology

Physiology of the functional organization of the gastrointestinal (GI) tract at all levels from the cell to the intact system; movement of nutrients from gut to other organs and integrative physiology of energy flux; immunology of the gut with emphasis on B-lymphocytes and mast cells; relevance of basic physiological processes to experimental medicine, pathophysiology and therapeutics.
637.01. Organization and Function of the GI Tract

Prerequisites: Consent of the Faculty.

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Medical Science 638 H(3-0)

Mucosal Pathophysiology

An independent study course that focuses on the physiology and pathophysiology of the gastrointestinal tract, lung and other mucosal tissues. A particular emphasis will be placed on inflammatory processes in these tissues, and how they contribute to symptom generation and tissue dysfunction. Involves independent research on the part of the students, small group tutorials, written assignments and laboratory exercises. The course will be divided into three sections.

Note: Medical Science 637.01 recommended.

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Medical Science 639 H(3-0)

Immunology

Introductory and advanced courses in immunology that cover humoral and cellular immunity and the inflammatory response at the cellular, molecular, and whole organism level. Basic mechanisms that lead to immunity or to inflammatory responses. The contribution of immunological and inflammatory processes in the immunopathogenesis of disease.
639.01. Principles of Immunology
639.02. Cellular and Molecular Immunology
639.03.Topics in Immunology
639.04. Inflammation

Prerequisites: Consent of the Faculty.

Note: Credit for both Medical Science 639.01 and 755.01 will not be allowed.

Note: Credit for both Medical Science 639.02 and 641.01 will not be allowed.

Note: Credit for both Medical Science 639.03 and 641.03 will not be allowed.

Note: Credit for both Medical Science 639 and 639.04 will not be allowed.

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Medical Science 641 H(3-0)

Genetics

Advanced courses that provide in depth coverage of the research discipline of genetics, including the areas of cytogenetics, genomics, metabolic genetics, mouse genetics, population genetics, and human and medical genetics.
641.01. Advanced Genetics I
641.02. Advanced Human Cytogenetics
641.03. Advanced Genetics II
641.04. Genomics

Prerequisites: Consent of the Instructor.

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Medical Science 643 H(3-2)

Biostatistics

Focuses on the key methods necessary to understand and critically interpret results from common biostatistical analyses, as well as, being able to analyze data using computer software. Medical Science

643.01 introduces the fundamental concepts of summarizing data and statistical inference, including graphical displays, hypothesis testing, p-values, confidence intervals, and sample size determination. Medical Science

643.02 extends the fundamental concepts to modelling health outcomes using modern regression analysis techniques. Logistic and linear regressions, and their extensions, are covered in detail. Medical Science
643.03 broadens the techniques to include generalized linear models (GLM), generalized additive models (GAM), Poisson regression, generalized estimating equations (GEE), and proportional hazards regression. In all three courses, students gain hands-on experience analyzing data using statistical software.

643.01 Biostatistics I: Essentials of Biostatistics

643.02 Biostatistics II: Models for Health Outcomes.
643.03. Biostatistics III: Models for Repeated Measures Studies and Time-to-Event Studies

Prerequisites: Medical Science 643.02 and 643.01 or a graduate-level introductory course in (bio)statistics. Medical Science 643.03 and Medical Science 643.02.

Note: Medical Science 643.01: While there are no formal prerequisites, good quantitative and mathematical skills are an asset.

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Medical Science 644 H(3-0)

Introduction to Community Health Sciences

For students entering the Department of Community Health Sciences; an introduction to the Department and a general orientation concerning the education and research programs in Community Health.

Prerequisites: Consent of the Instructor.

NOT INCLUDED IN GPA

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Medical Science 645 H(3-0)

Health Care

The components of the health care system; the structure and function of the Canadian health care system and issues in the organization of health care delivery; environmental and psycho-sociocultural factors in health, illness and health care; specific problems and issues in health care.
645.01. Systems of Health and the Health Care System
645.02. Determinants of Health
645.03. Environmental Health
645.06. Health Protection
645.10. Leadership in Health Care Organizations
645.13. Health of Canadian Aboriginal Peoples
645.15. Health Policy: Policy Issues in the Canadian Health Care System
645.16. Global Health and Development
645.17. Introduction to the Legal and Ethical Framework of Health Care in Canada

Prerequisites: Consent of the Faculty.

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Medical Science 646 H(3S-0)

Seminars in Occupational Health and Medicine

Current issues in occupational health and medicine; topics to be based on a pre-course survey.

Prerequisites: Consent of the Instructor.

NOT INCLUDED IN GPA

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Medical Science 647 H(3-2)

Epidemiology

Principles and methods of descriptive, analytic and experimental epidemiology. Epidemiological methods specific to certain health conditions and the preventive strategies available for various health conditions. 647.01. Fundamentals of Epidemiology 647.05. Epidemiology of Aging 647.07. Research in Infection Control & Hospital Epidemiology 647.09. Epidemiology of Chronic Diseases 647.10. Surveillance 1: Data Handling for Infection Control 647.11. Surveillance 2: Principles of Surveillance 647.12. Introduction to Population Health 647.15 Clinical Epidemiology

Prerequisites: Medical Science 643.01 or consent of the Faculty.

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Medical Science 649 H(1-3)

Practicum in Community Health Sciences

Clinical or laboratory-based practicum for students enrolled in certain programs of the Department of Community Health Sciences.
649.01. Practicum in Community Medicine
649.02. Practicum in Hospital Epidemiology

Prerequisites: Consent of the Faculty.

NOT INCLUDED IN GPA

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Medical Science 651 H(3-0)

Health Promotion

"Health promotion is the process of enabling people to increase control over and to improve their health." The following courses are intended to assist graduate students in putting this Ottawa Charter definition into practice.
651.01. Planning for Health Promotion
651.02. Health Promotion for Women
651.03. Community Interventions: Theory, Research and Practice

Prerequisites: Consent of the Instructor.

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Medical Science 653 H(3-0)

Public Health

Courses in the public health specialization prepare students for public health research and practice. The courses have been chosen to represent the unique functions that public health professionals perform in the health system and in society in a variety of settings from local to international. Required courses prepare students to enhance the health of populations by exploring health issues, needs, and capacities of defined populations, planning interventions, and supporting services that protect and promote the public's health. Elective courses are available to address the student's unique interests.
653.01. Foundations of Public Health

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Medical Science 657 H(3-0)

Telehealth and E-health

These online courses explore many aspects of e-health, beginning with an initial focus on telehealth. They reflect a range of practice-based activities and research areas in e-health including business plan development, implementation and evaluation of clinical and learning applications.
657.02. e-Health Sustainability: From Business Case to Policy Development
657.03. Evaluation of e-Health Initiatives

Prerequisites: Consent of the Faculty.

Note: These are online courses.

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Medical Science 659 H(3-2)

Methods in Health Research

An introduction to research design, sampling, measurement, data collection and data analysis applied to health research including evaluation research.
659.02. Health Research Methods
659.03. Health Program Planning and Evaluation
659.04. Introduction to Clinical Trials
659.05. Qualitative Health Research
659.06. Decision Analysis in Health Care Economic Evaluation
659.07. Administrative Data Analysis Methodology

Prerequisites: Medical Science 643.01 or consent of the Faculty.

Note: Credit for both Medical Science 659.05 and Sociology 713.01 will not be allowed

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Medical Science 660 F(3-1.5)

On-line Basic Infection Control

Provides novice Infection Control Professionals (ICPs) with the basic knowledge, tools and strategies needed to do Infection Control in a broad range of health care environments from health care institutions to the community. The purpose of this entry to practice course is 1) to identify and describe the scope of infection prevention and control problems and issues for novice ICPs and 2) to examine and integrate their current expertise with the basic knowledge, tools and strategies needed to examine problems and develop practical solutions in Infection Control.

Prerequisites: Consent of Instructor.

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Medical Science 661 H(3-0)

Science Value and Philosophy

Philosophical issues which fall into two categories: the Nature of Scientific Inquiry and Science and Moral Value.

Prerequisites: Consent of the Instructor.

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Medical Science 663 H(3-0)

(Kinesiology 663) (Mechanical Engineering 663)

Advanced Biomechanics

Theoretical and applied aspects of biomechanics in the acquisition and performance of sport skills.

Prerequisites: Consent of the Faculty.

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Medical Science 670 F(0-6)

Practicum in Biomedical Technology

A laboratory-based full course carried out in an academic or industrial setting for a period of at least ten weeks. Students have an opportunity to apply the principles and methods of investigation learned during the Master of Biomedical Technology program and carry out related research in one of the Faculty of Medicine laboratories or in an industrial setting.

Prerequisites: Consent of the Faculty.

Note: Completion of all other course requirements in Master of Biomedical Technology program is normally required prior to registration for this course.

NOT INCLUDED IN GPA

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Medical Science 671 H(0-6)

Techniques in Medical Science

Introduction to the theory of operation of electronic devices commonly used in biophysical studies including principles of amplifiers and filters, micro- and patch electrode techniques and computer-laboratory interfacing.

Prerequisites: Consent of the Faculty.

MAY BE REPEATED FOR CREDIT

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Medical Science 672 H(2-0)

Biotechnology Business Aspects

Aspects involved in taking an original scientific idea or discovery all the way to a start-up company will be covered. Lecturers discuss commercialization, venture capital, business plan, patents and law, marketing.

Prerequisites: Consent of the Biomedical Technology Graduate Coordinator.

Note: Admission to the Master of Biomedical Technology program is required for enrolment in this course.

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Medical Science 673 H(0-3S)

Careers in Biotechnology

A series of talks and workshops designed to provide students with practical knowledge of the biotechnology industry. In collaboration with the Áù¾ÅÉ«Ìà Career Services, the course covers personal and professional development planning, resume writing, networking, negotiation and interviewing skills and job search strategies specifically for the biotechnology field. This course runs during the fall and winter block weeks with additional retreat days throughout the year.

Note: Admission to the Master of Biomedical Technology program is normally required for enrolment in this course.

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Medical Science 674 F(3-0)

Integrated Systems Course

The principles of physiology, pharmacology, microbiology and immunology. Lectures in the two courses are in parallel and fully integrated. Both courses are required components of the MBT program. The goal of the course, with an emphasis on molecular mechanisms in health and disease, is to provide students with the skills to interface with individuals in these disciplines in the biotechnology industry. Complemented by demonstrations, tours and special lectures that provide industry perspectives in these disciplines.
674.01. Principles of Physiology and Pharmacology
674.02. Principles of Microbiology and Immunology

Prerequisites: Consent of the Faculty.

Note: Admission to the Master of Biomedical Technology program is normally required for enrolment in either section of this course.

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Medical Science 675 H(2-3T)

Bioinformatics Resources for the Biologist

This introductory graduate level course will familiarize biologists with algorithms and search engines used to analyze nucleic acid and protein sequences and structures.

Prerequisites: Consent of the Faculty.

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Medical Science 677 H(1-6)

Directed Study in Biomedical Technology

Lectures, seminars, term papers or training in theoretical and/or laboratory methods at the advanced level in biomedical technology or medical sciences.

Prerequisites: Consent of both the faculty member who will supervise and the MBT faculty member who will co-supervise the chosen study.

Note: Admission to the Master of Biomedical Technology program is required for enrolment in this course.

MAY BE REPEATED FOR CREDIT

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Medical Science 678 H(1-6)

Project in Biomedical Technology

Conduct a business or laboratory-based project throughout the year. Business-based projects include running a business, doing market research for companies or working with their business mentor. Laboratory-based students will get credit for the laboratory components that complement the core program with the project orientated around their new drug.
678.01. Laboratory-Based Project
678.02. Business-Based Project

Prerequisites: Consent of the Faculty.

Note: Admission to the Master of Biomedical Technology program is required for enrolment in this course.

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Medical Science 679 H(3-0)

(Economics 679)

Health Economics I

Applies basic concepts from economics to the examination of health and health care policy issues such as why we have the kind of health care system we have, various aspects of health care reform, promotion of health, and evaluation in interventions.

Prerequisites: Consent of the Faculty.

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Medical Science 683 H(3-0)

The Biology and Therapy of Human Cancer

An examination and discussion of current knowledge of the molecular and cellular biology of human cancer and the scientific basis of cancer therapy. Offered in a modular format: each course will consist of one required module and two elective modules. Students can choose the elective modules from a list that is specific for each course. Modules will emphasize student presentations, critical evaluation, and discussions of current and seminal research papers on the module topic. Refer to the Southern Alberta Cancer Research Institute website at www.sacri.ucalgary.ca for more information.
683.01 Cancer Pathology, Epidemiology and Therapy
683.02. Molecular Mechanisms of Cancer
683.04. Cell Biology of Cancer

Prerequisites: Consent of the Faculty.

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Medical Science 685 H(3-3)

(Mechanical Engineering 685)

Biomechanics of Human Movement

Introduction to the measuring methods (accelerometry, goniometry, film and film analysis, video systems) of biomechanical analysis of human movement (force and force distribution). Description of the mechanical properties of bone, tendon, ligaments, cartilage, muscles, and soft tissues. The relation between structure and function of biomaterials. Introduction in descriptive analysis of human movement.

Prerequisites: Consent of the Faculty.

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Medical Science 689 H(3-0)

Medical Imaging

Introduction to the theory and practical applications of medical imaging. Specific courses focus on an overview of modern diagnostic imaging techniques (689.01), as well as advanced study of specific techniques including magnetic resonance imaging (689.02) and medical image processing (689.03), and molecular imaging (689.04).
689.01. Medical Imaging Techniques
689.02. Advanced Magnetic Resonance Imaging
689.03. Advanced Medical Image Processing
689.04. Advanced Molecular Imaging
689.99. Medical Imaging Project

Prerequisites: Consent of the Faculty. Medical Science 689.01 should be taken prior to the advanced courses.

Note: Courses are open to interested graduate students in medicine, engineering, and science and to appropriately prepared undergraduate students enrolled in computer engineering, electrical engineering, and physics.

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Medical Science 701 H(3-0)

Advanced Topics in Reproductive Health

A series of topics, ranging from basic sciences to clinical topics (including ethical issues) to increase awareness and comprehension regarding current issues in reproductive health.

Prerequisites: Interest in reproductive health/reproductive biology. Consent of course co-ordinator and student's supervisor, if applicable.

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Medical Science 703 H(2-6)

Human Anatomy: Concepts, Exploration and Teaching

Introductory course for graduate students with an interest in mammalian morphology to human cadaver dissection, human anatomy concepts and teaching strategies within the medical professional curriculum. Weekly lectures and discussions supplement a cadaver dissection-based course intended for students interested in pursuing an academic career in a medically related field.

Prerequisites: Should have some previous experience with dissection. Consent of the instructors.

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Medical Science 705 H(3-0)

Advanced Methods in Health Research

Advanced health research designs (both quantitative and qualitative) and measurement techniques.

Prerequisites: Medical Science 659.02.

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Medical Science 706 H(3-0)

Theory and Practice of Family Therapy

Overview of different family therapy approaches focusing on systemic assessment and systemic intervention through therapeutic interviewing. The development of student knowledge and skills in family therapy utilizing social constructionist, narrative, systemic, collaborative, and pro-feminist ideas while fostering the professional identity of the therapist.
706.01. Theory and Practice of Family Therapy I: Systemic Approaches
706.02. Theory and Practice of Family Therapy II: Postmodern Approaches

Note: This course is open to registered graduate students in medicine and the mental health professions, all others will require consent of the instructor.

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Medical Science 707 H(2S-12)

Family Therapy Practicum

The development of conceptual and experiential expertise in working therapeutically with families.
707.01. Family Therapy I.
707.02. Family Therapy II

Prerequisites: Consent of the Faculty.

NOT INCLUDED IN GPA

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Medical Science 709 H(3-2)

Advanced Epidemiology

Topics to include causal inference, epidemiologic measures, induction latent period, internal and external validity, control of confounding variables and interaction between study factors.

Prerequisites: Medical Science 647.01.

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Medical Science 711 H(3S-0)

Systematic Reviews and Meta-Analysis

Exposes students to all steps involved in the conduct of a systematic review and meta-analysis.

Prerequisites: Medical Science 643.01, 643.02, 647.01 and 659.02, or consent of Instructor.

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Medical Science 713 H(0-3T)

Topics in Mountain Medicine and High Altitude Physiology

A tutorial-based course focused on high altitude medicine and physiology. The aim of the course is to introduce the students to the physiological adaptations of, and pathophysiology associated with, the hypoxia of altitude. Students will be introduced to several diseases associated with the hypoxia of high altitude (i.e., Acute Mountain Sickness; High Altitude Pulmonary Edema, High Altitude Cerebral Edema), and the pathophysiology underlying these diseases.

Prerequisites: Consent of Instructor.

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Medical Science 717 H(150 hours)

Functional Genomics Technologies

An intensive "hands on" laboratory course supplemented with lectures that provides experience and theory underlying current techniques used in functional genomics research. Methods include DNA microarrays, bioinformatics analysis of DNA and protein sequences, retro-recombinant screening, gene marker and mutation analysis, gene product interactions and yeast two-hybrid screens, site-specific mutagenesis, mammalian expression systems and in situ hybridization. More conventional molecular biology methods involving plasmid preparation, Northern and Southern blotting techniques, PCR technology, restriction digestions, subcloning of DNA fragments, and others are included.

Prerequisites: Registration in the Master of Biomedical Technology program or one of Medical Science 537, 609.01, 609.02, 613.05 or equivalent, and consent of the Faculty.

Corequisites: Prerequisite or Corequisite: Medical Science 537 (Biochemistry 537) or equivalent.

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Medical Science 721 H(3-0)

Biochemistry and Molecular Biology

Historical and recent developments in analysis of eukaryotic genomes and control of gene expression, chromosome structure, bioinformatics, sequencing, proteomics, regulatory networks, metabolomics and related technologies and their applications to the study of human disease.

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Medical Science 731 H(1S-4)

Medical Education

The design, planning, teaching and evaluation of courses in the health science disciplines. Practical experience in teaching methods and curriculum development. Intended for graduate students, faculty and resident physicians, and approved for study credit by the College of Family Physicians of Canada.

Prerequisites: Consent of the Faculty.

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Medical Science 733 H(3-1)

Research Design and Statistics in Medical Education

Research design and statistical analysis including a broad overview of the variety of methods for research in medical education and related sciences. There is both a theoretical basis in lectures and seminars as well as applied approaches in laboratory exercises. A variety of research tools will be explored and utilized.

Prerequisites: Consent of the Instructor.

Note: Admission to the Medical Education specialization of the Medical Science graduate program is normally required for enrolment in this course.

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Medical Science 735 H(3-0)

Teaching Methods in the Medical Sciences

Examines traditional and innovative methods used in medical and science education and clinical teaching to enhance student and practitioner knowledge, skills and attitudes. Discussions and presentations will focus on the role of the teacher and teaching strategies that include the lecture, small group teaching, inquiry and problem solving methods, reflective tools, simulation, surgical skills, computer based instruction, bedside learning, one on one teaching and self-directed learning. The content will be presented within the context of contemporary research, practice and educational theory. Participants will be expected to identify, critique literature, and prepare instructional activities that link research and theory to practice.

Prerequisites: Consent of Instructor.

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Medical Science 737 H(3-0)

Curriculum Design and Evaluation in the Medical Sciences

Presents an overview of the key elements of curriculum design and evaluation within the context of contemporary medical education research, learning and teaching theory, and teaching. Through classroom and electronic discussion, reading and assignments, participants will explore learning needs, objectives, the selection of teaching methods, the identification of resources, the implementation and monitoring of curriculum and evaluation.

Prerequisites: Consent of Instructor.

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Medical Science 739 H(3-0)

Medical Education Measurement

Focuses on the assessment issues related to the measurement of student achievement, competency, and performance in educational settings. The principles of Classical Test Theory, Item Response Theory, and Generalizability Theory will be introduced and explored through both formal lectures and computer lab activities. Specifically, the course will focus on the measurement issues and concerns related to undergraduate and post-graduate medical education programs.

Prerequisites: Consent of Instructor.

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Medical Science 751 H(3-0)

Topics in Medical Science

751.02. Cellular and Molecular Pathogenic Mechanisms of Diabetes
751.03. Biostatistics
751.07. The Physiological Development of the Fetus and Newborn
751.09. Ion Channel Diseases
751.18. Neural Control of Posture and Movement
751.30. Transdisciplinary Bone and Joint Health
751.31. Joint Injury and Disease Biomechanical Focus
751.41. Critical Perspectives in Proteomics.

Prerequisites: Consent of the Faculty.

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Medical Science 755 H(1-6)

Directed Study

Lectures, seminars, term papers or training in theoretical and/or laboratory methods at the advanced level in the medical sciences.

Prerequisites: Consent of faculty member who will supervise the chosen study.

MAY BE REPEATED FOR CREDIT

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In addition to the numbered and titled courses shown above, the department may offer advanced level graduate courses specifically designed to meet the needs of individuals or small groups of students at the advanced doctoral level. These courses are numbered in the series 800.01 to 899.99. Such offerings are, of course, conditional upon the availability of staff resources.