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About the ɫ
 Graduate Studies Calendar 2014-2015 Courses of Instruction Course Descriptions C Cellular, Molecular and Microbial Biology CMMB
Cellular, Molecular and Microbial Biology CMMB
CMMB 505 511 519 523 527 531 543 545 549 561 563 565 567 637
 

Instruction offered by members of the Department of Biological Sciences in the Faculty of Science.

Department Head - R.M.R. Barclay
 
Cellular, Molecular and Microbial Biology 505       Advanced Developmental Biology
In-depth analyses of the current literature in developmental biology. Emphasis will be on the co-ordinated regulation of gene expression during development.
Course Hours: H(3S-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 403.
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Cellular, Molecular and Microbial Biology 511       Molecular Biology and Genetics
The concepts of molecular biology as they apply to genetics. Application of current methodology to the understanding of the genetics of prokaryotes, lower and higher eukaryotes (for example: fungi, yeasts, trypanosomes, plants and animals). Genomic organization and function of subcellular organelles such as mitochondria and chloroplasts will also be considered in detail. The mechanism(s) of regulation of gene expression will be discussed in relation to nuclear as well as organelle genomes.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 519       Advanced Cell Biology
In-depth analysis of current literature in cell biology. Topics include subcellular organization and dynamics, cell signalling and differentiation, protein and RNA trafficking, and other aspects of eukaryotic cell biology.
Course Hours: H(3-0)
Prerequisite(s): Biology 311 and 331 and one of Biochemistry 401 or 443.
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Cellular, Molecular and Microbial Biology 523       DNA Genomes and RNA Function
An examination of information storage and gene expression in prokaryotes and eukaryotes. Biochemical mechanisms of gene expression and regulation in bacteria. Genome sequencing projects and a survey of genome structure and content across domains of life. Topics in eukaryotic gene expression. The diverse roles played by RNA, from information molecules to structural scaffolds to ribozymes.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 527       Immunology
Comprehensive overview of the immune system and how immune responses are generated and regulated in the context of infectious diseases. Topics include both fundamental cellular and molecular immunology. Dysregulated responses, such as autoimmunity, immunodeficiencies, transplants, and allergies will also be covered.
Course Hours: H(3-3)
Prerequisite(s): Biology 311 and 331 and Cellular, Molecular and Microbial Biology 343 and one of Biochemistry 401 or 443.
Notes: Enrolment in this course may be limited. See Program Details in the Faculty of Science section of this Calendar.        
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Cellular, Molecular and Microbial Biology 531       Topics in Cellular Interactions
An exploration of selected topics concerning cell-cell interactions and the interactions of cells with their environment during development, differentiation and disease. Multidisciplinary approaches will be presented, using discussions of seminal research and critical analysis of current literature. Potential topics include cell junctions, cell signaling, cytoskeletal organization, stroma, extracellular matrix remodelling and stem cells.
Course Hours: H(3-0)
Prerequisite(s): Biology 331 and one of Biochemistry 401 or 443 or 431.
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Cellular, Molecular and Microbial Biology 543       Environmental Microbiology
Focuses on understanding the interactions of micro-organisms with their environment. Roles of micro-organisms in nutrient cycling, biological control, and biodegradation will be discussed. The use of molecular approaches to identify and characterize microbial communities, and to understand the precise nature of microbial interactions with abiotic and biotic environments will be emphasized. Special topics will include plant-microbe and animal-microbe symbiosis, extreme environments and biotechnological applications of environmental microbiology.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 545       Petroleum Microbiology
Microorganisms can contribute to a more sustainable energy future. Their impact and roles in the fossil fuel industry will be reviewed. Topics will include oilfield souring, biocorrosion, biodegradation, enhanced recovery, upgrading, and bioremediation of contaminated sites.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 549       Microbial Genetics
The genetics and genomics of prokaryotes. Topics will include recombination, mechanisms of genetic exchange, analysis of genes and genomes, and genome evolution. Selected current topics in bacterial genetics will also be covered.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 561       Cancer Biology
Advances in methodology and in theoretical concepts have permitted continuing breakthroughs in our understanding of the organismal, cellular and molecular biology of cancer cells, and in the development of novel strategies for cancer prevention, diagnosis and treatment. These advances will be presented in a comprehensive overview of cancer including issues of demographics and incidence, causation and detection, origins and progression and therapeutic approaches. Emphasis will be placed on the cell and molecular biology of cancer and on the interaction of the cancer cell with the host organism.
Course Hours: H(3-0)
Prerequisite(s): Biology 331 and Cellular, Molecular and Microbial Biology 411 and one of Biochemistry 401 or 443.
Also known as: (Medical Science 561)
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Cellular, Molecular and Microbial Biology 563       Microbial Diversity
An overview of microbial diversity, the evolutionary mechanisms that give rise to it, and the methods used to study it. Topics may include: microbial systematics; characterizing the last universal common ancestor of life; estimating global microbial diversity; “unculturable” microbes and molecular DNA-based methods used to study them in nature; modern cultivation techniques; comparative genomics of microbial species; environmental metagenomics; microbial biogeography and speciation and gene flow in microbial communities.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 565       Advanced Topics In Pathogenic Microbiology
The course will provide a fuller understanding of bacterial diseases using a systems approach and illustrating key paradigms via the consideration of specific pathogens. Topics include: strategies for bacteria surviving host immune responses, bacterial invasion strategies, opportunistic infections, disease Pathogenesis, and antibiotic resistance, challenges of dealing with emerging infections. Lectures, small group interactive sessions, specified readings.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 and 431.
Also known as: (Medical Science 565)
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Cellular, Molecular and Microbial Biology 567       Advanced Topics In Immunology
New and emerging themes in immunology, with an emphasis on disease processes such as inflammation in the gut, kidney and lung. Topics include: innate immunity, the inflammasome, sterile inflammation, process and mechanism of immune cell recruitment in different tissues, T cell biology, B cell biology, regulatory immune cells, mucosal immunity, airways responses to virus, mechanisms of food allergies, inflammatory bowel disease. Lectures, small group interactive sessions, specified readings.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 527.
Also known as: (Medical Science 567)
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Graduate Course

Enrolment in any graduate course requires consent of the Department.

Only where appropriate to a student's program may graduate credit be received for courses numbered 500-599.

600-level courses are available with permission to undergraduate students in the final year of their programs.

 
Cellular, Molecular and Microbial Biology 637       Advanced Topics in Molecular Microbiology
Techniques and discussion of recent literature in molecular microbiology. Topics covered will vary from year to year, but could include bioinformatics, genomics, mutagenesis, advanced microscopy techniques, proteomics, vectors and cloning techniques, gene expression, and over-expression of proteins, as they relate to the study of prokaryotic systems. Course content will be tailored to the interests of the graduate students enrolled in the class in a given year.
Course Hours: H(3-0)
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