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Áù¾ÅÉ«Ìà Calendar 2009-2010 COURSES OF INSTRUCTION Course Descriptions B Biomedical Engineering BMEN
Biomedical Engineering BMEN

Instruction offered by members of the Schulich School of Engineering and Kinesiology.

Associate Dean (Academic & Planning) – R. Brennan

Director, Centre for Bioengineering Research and Education – J. Ronsky

Biomedical Engineering 103       Biomedical Engineers and Technology in Health Care
Factors in modern health care provision, economic and social constraints, methods for determining efficacy of treatment (outcome measures), health technology assessment and decision-making, considerations of quality of life, methods for determining local, national and global needs, roles for the Biomedical Engineer in healthcare.
Course Hours:
Q(20 hours)
Also known as:
(formerly Biomedical Engineering 003)
NOT INCLUDED IN GPA
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Senior Courses
Biomedical Engineering 309       Anatomy and Physiology for Engineers
Physiological terminology and anatomical planes of reference; cell biology and physiology; includes structure and function of musculoskeletal, cardiac, nervous, gastrointestinal and respiratory tissues and systems; diseases and disorders of those systems; design constraints for bioengineering products.
Course Hours:
H(3-3/2)
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Biomedical Engineering 319       Applied Statistics for the Experimental Sciences
Presentation and description of data, introduction to probability theory, Bayes theorem, discrete and continuous probability distributions, estimation, sampling distributions, tests of hypotheses on means, variances and proportions, simple linear regression and correlation, multivariate analysis, power calculations and statistical significance for study design, analysis of variance, additional models of regression analysis. Applications are chosen from bioengineering examples.
Course Hours:
H(3-1.5T)
Prerequisite(s):
Applied Mathematics 219.
Antirequisite(s):
Note: Credit for both Biomedical Engineering 319 and Engineering 319 will not be allowed.
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Biomedical Engineering 327       Electrical Circuits for Biomedical Engineers
Definition of linear elements, independent and dependent sources, sign conventions; basic circuit laws, simple resistive circuits; node and mesh analysis. Thevenin, Norton and other theorems; inductance and capacitance. AC circuit analysis, impedance, admittance, phasor diagrams; average and effective values of waveforms, real, reactive and complex power, power calculations; mutual inductance, ideal transformer, introduction to balanced three-phase circuits, power calculation in three-phase circuits. The tutorial and laboratory will introduce basic principles of sensors and measurement in a biomedical context. Includes signal amplification and filtering and analog-to-digital conversion.
Course Hours:
H(3-1T-3/2)
Prerequisite(s):
Physics 259.
Antirequisite(s):
Note: Credit for both Biomedical Engineering 327 and any of Engineering 325, Electrical Engineering 329 or 341 will not be allowed.
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Biomedical Engineering 405       Biological Tissue and System Mechanics
To understand the constitutive and structural behaviour of complex biological tissue: mechanical and electro-chemical properties of biological tissues, nonlinear and time-dependent behaviour, functional adaptation to load, multi-phasic materials, anisotropic and composite materials, structural and micro-structural behaviour, hierarchical modelling from system to tissue to cell, failure theories.
Course Hours:
H(3-1T-2)
Prerequisite(s):
Engineering 317, Biomedical Engineering 309.
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Biomedical Engineering 407       Cell Culture and Tissue Engineering
Mammalian cell culture, including nutrient metabolism, growth kinetics and scale up to bioreactors. Cell adhesion, cell aggregation, cell motility. Forces on cells, stress and strain, fluid shear. Mass transfer in tissues, extra-cellular matrix and tissue microenvironments, biomaterials, artificial organs. Therapeutic molecule production from genetically engineered cells.
Course Hours:
H(3-1T-2)
Prerequisite(s):
Biomedical Engineering 309.
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Biomedical Engineering 409       Bioelectricity
The generation, transmission, and measurement of electrical events generated by the excitable cells which compose the heart, brain, and muscle. Starting with the behaviour of ions in solution, a description of biologically generated electricity is built up to ultimately relate cellular activity to body surface potentials as measured by the electrocardiogram and electroencephalogram. Equivalent electrical circuit representations of biological structures are derived. Physiology specific to the organ being studied will be given.
Course Hours:
H(3-1T -2)
Prerequisite(s):
Chemistry 209, Biomedical Engineering 309, 327.
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Biomedical Engineering 500       Biomedical Engineering Research Thesis
A directed studies research project in an area of interest, directed by a project advisor/faculty member within the faculties of Engineering, Kinesiology, Science or Medicine. Includes a lecture component covering the scientific process, ethics, review of literature, and writing scientific proposals and manuscripts. The course culminates with a written thesis and presentation. Projects may involve experimental, analytic or computer modeling studies.
Course Hours:
M(1-8)
Prerequisite(s):
Final-year standing in the Engineering program of choice.
Notes:
Pre-term study is required.
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Biomedical Engineering 501       Biomedical Engineering Project
A directed studies project in an area of interest, supervised by a project advisor/faculty member within the faculties of Engineering, Kinesiology, Medicine, or Science. Includes a lecture component covering topics including the scientific process, ethics, review of literature, patent searches, market analysis, and technology evaluation. The project involves choosing a particular product, process or theory relevant to biomedical engineering, researching it and justifying its selection. A final report and presentation are required.
Course Hours:
H(1-2)
Prerequisite(s):
Final-year standing in the Engineering program of choice.
Notes:
Pre-term study is required.
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Biomedical Engineering 509       Introduction to Biomedical Imaging and Applications
Principles of various imaging modalities used in Biomedical engineering applications, including CT, MRI, ultrasound, PET, SPECT. Image processing operations: filtering, enhancement, feature extraction, pattern recognition and image reconstruction. Image registration and integration of different imaging modalities.
Course Hours:
H(3-2)
Prerequisite(s):
Applied Mathematics 307, Engineering 233, and one of Engineering 319, Biomedical Engineering 319, or Electrical Engineering 419.
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Biomedical Engineering 511       Biomaterials and Biocompatibility
Basic chemical and mechanical properties of biological and synthetic materials and their role in biological system health, dysfunction, and repair. Role of microstructure, material properties, and biocompatibility aspects in selection of biomaterials for medical or industrial applications. Incorporation of biomimetic concepts in material design. Topics may include artificial and tissue engineered products, implants, prostheses, biofilms, biosensors, and foreign body response.
Course Hours:
H(3-2)
Prerequisite(s):
Biomedical Engineering 309 and one of 405 or 407, or permission of the instructor.
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Biomedical Engineering 513       Photogrammetric Techniques for Reconstruction and Manipulation of Biomedical Data
Basic photogrammetric principles. Photogrammetric techniques for biomedical applications; image acquisition, camera calibration, bundle adjustment, conventional and x-ray imagery, accurate geometric measurements; multivariate least-squares estimation and object reconstruction from 2D and 3D imagery. Other photogrammetric techniques, including laser scanning, range cameras, and coded light projection. Applications in motion capture, implant measurement, facial measurement, and computer-assisted surgery.
Course Hours:
H(3-2)
Prerequisite(s):
Engineering 233, Applied Mathematics 219, Mathematics 211 , and one of Engineering 319 , Biomedical Engineering 319, or Electrical Engineering 419 .
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Biomedical Engineering 515       Bioengineering Methods in Systems Biology and Physiology
Concepts from systems theory, differential equations, and stochastic processes applied to physiological and biological systems. Experimental and computational approaches to the study of gene expression and gene networks. Use of quantitative model-based approaches for integrative analysis of physiological and biological functions. Case studies of applications to disease mechanisms and the drug discovery process.
Course Hours:
H(3-2)
Prerequisite(s):
Applied Mathematics 307.
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Biomedical Engineering 517       Biomedical Device Development
Medical device development and how it differs from other types of device development. Identification of market needs. Quality system requirements. Requirements for regulatory approval, including risk classifications, testing standards and human factors considerations. Importance and timing of intellectual property protection, especially patents. Commercialization considerations and pathways. Financing of new medical devices. Medical device industry-specific examples will be presented.
Course Hours:
H(3-2)
Prerequisite(s):
Final-year standing in the Engineering program of choice.
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Biomedical Engineering 519       Special Topics in Biomedical Engineering
Current topics in Biomedical engineering.
Course Hours:
H(3-2)
Prerequisite(s):
Consent of the BMES Director or designate.
MAY BE REPEATED FOR CREDIT
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Graduate Courses
Biomedical Engineering 601       Fundamentals of Biomedical Engineering
An introduction to biology, biochemistry, anatomy, physiology, engineering fundamentals, and biostatistics for biomedical engineers. Detailed discussion on current biomedical engineering topics, including current local and international research and industry, with an emphasis on local strengths.
Course Hours:
H(3-0)
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Biomedical Engineering 603       Frontiers of Biomedical Engineering
An introduction to research in biomedical engineering, experimental design, preparation and review of research proposals, technical (oral and written) communication to diverse audiences, obtaining employment in industry, academia.
Course Hours:
H(3-0)
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Biomedical Engineering 605       Research Seminars in Biomedical Engineering
Reports of studies of the literature or of current research.
Course Hours:
Q(1.5S-0)
NOT INCLUDED IN GPA
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Biomedical Engineering 607       Research Seminars in Biomedical Engineering
Reports of studies of the literature or of current research.
Course Hours:
Q(1.5S-0)
NOT INCLUDED IN GPA
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Biomedical Engineering 609       Anatomy and Physiology for Biomedical Engineers
Advanced instruction on human skeletal structure, types of connective tissues, structure of joints, muscle and organ structure and function, cardiac physiology, blood properties and flow, introduction to autonomous nervous system, and disorders of the musculoskeletal system. Other topics will be covered dependent on the interests of the instructor and students.
Course Hours:
H(3-3/2)
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Biomedical Engineering 619       Special Problems in Biomedical Engineering
Designed to provide graduate students, especially at the PhD level, with the opportunity of pursuing advanced studies in particular areas under the direction of a faculty member.
Course Hours:
H(3-1)
MAY BE REPEATED FOR CREDIT
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